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Anti-KRT18 Antibody EPR1611
Also for KRT18 (NM_000224)
|A synthetic peptide corresponding to residues in human Cytokeratin 18 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; ICC/IF: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens keratin 18 (KRT18), transcript variant 1|
|Keratin polypeptides 8 and 18 (K8/18) are intermediate filament phosphoglycoproteins that are expressed preferentially in glandular epithelia. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells (1-3). Together with actin microfilaments and microtubules, keratin filaments make up the cytoskeletons of vertebrate epithelial cells, forming alpha-helical coiled-coil dimers which associate laterally and end-to-end to form 10-nm diameter filaments (4).|
EGFR1 Signaling Pathway
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Western blot - Anti-Cytokeratin 18 antibody [EPR1611]; All lanes : Anti-Cytokeratin 18 antibody [EPR1611] at 1/10000 dilution.Lane 1 : MCF-7 cell lysates.Lane 2 : A431 cell lysates.Lane 3 : HeLa cell lysates.Predicted band size : 48 kDa.
Immunocytochemistry/ Immunofluorescence - Anti-Cytokeratin 18 antibody [EPR1611]; Immunofluorescence analysis of HeLa cells labelled with ab133302 at 1/100 dilution.