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Home Antibody All anti-KREMEN1 antibodies

Anti-KREMEN1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320040
  • Rabbit Polyclonal KREMEN1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC422073) , 20ug
100ug 325 In Stock
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WB(1)
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Also for KREMEN1 (NM_001039570)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IHC, IF
BufferKREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KREMEN1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens kringle containing transmembrane protein 1 (KREMEN1), transcript variant 3
Alternative NameKREMEN; KRM1
Database LinkNP_001034659
FunctionKREMEN1 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes.
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KREMEN1 in rat small intestine tissue lysate with KREMEN1 antibody at (A) 0.125 and (B) 0.25 ug/mL

 

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