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Home Antibody All anti-KPNA4 antibodies

Anti-KPNA4 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319674
  • Rabbit Polyclonal KPNA4 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400822) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for KPNA4 (NM_002268)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenKPNA4 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA4.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, ICC: 2.5 ug/ml, IF: 20 ug/ml
BufferKPNA4 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KPNA4 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens karyopherin alpha 4 (importin alpha 3) (KPNA4)
Alternative NameIPOA3; QIP1; SRP3
Database LinkNP_002259
Entrez Gene 3840 Human
Entrez Gene 16649 Mouse
Entrez Gene 361959 Rat
FunctionKPNA4 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-α-induced nuclear import of NF-κB. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KPNA1 in Hela cell lysate with KPNA1 antibody at 1ug/mL.
IHC Image
Immunocytochemistry of KPNA4 in HeLa cells with KPNA4 antibody at 2.5 µg/mL.
IF Image
Immunofluorescence of KPNA4 in HeLa cells with KPNA4 antibody at 20 µg/mL.

 

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