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Home Antibody All anti-KPNA1 antibodies

Anti-KPNA1 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319671 Rabbit Polyclonal KPNA1 Antibody 100ug $325 In Stock
LC400827 KPNA1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for KPNA1 (NM_002264)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenKPNA1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 2.5 ug/ml, IF: 20 ug/ml
BufferKPNA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KPNA1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens karyopherin alpha 1 (importin alpha 5) (KPNA1), transcript variant 1
Alternative NameIPOA5; NPI-1; RCH2; SRP1
Database LinkNP_002255
Entrez Gene 3836 Human
Entrez Gene 16646 Mouse
Entrez Gene 288064 Rat
FunctionKPNA1 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of Ebola and influenza.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of KPNA1 in Hela cell lysate with KPNA1 antibody at 1ug/mL.
Immunofluorescence of KPNA1 in K562 cells with KPNA1 antibody at 20 ug/mL.


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