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Home Antibody All anti-KLRC1 antibodies

Anti-KLRC1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308317 Rabbit Polyclonal antibody to KLRC1 (killer cell lectin-like receptor subfamily C, member 1) 100ul $325 In Stock
LC431023 KLRC1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1 and 45 of KLRC1 (Uniprot ID#P26715)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Rhesus Monkey, Chimpanzee) Concentration0.54mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 26kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rhesus Monkey (100%), Chimpanzee (100%)

Reference Data

Target NameHomo sapiens killer cell lectin-like receptor subfamily C, member 1 (KLRC1), transcript variant 3
Alternative NameCD159A; NKG2; NKG2A
Database LinkNP_998823
Entrez Gene 3821 Human
Entrez Gene 574146 Monkey
FunctionNatural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq]
Related PathwayTransmembrane Antigen processing and presentationNatural killer cell mediated cytotoxicityGraft-versus-host disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A431 . B: Hep G2 . 12% SDS PAGE. NKG2-A (CD159a) antibody. TA308317 diluted at 1:1000.
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KLRC1 antibody [N1N2], N-term detects KLRC1 protein at cytosol on H1299 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H1299 xenograft. KLRC1 antibody [N1N2], N-term (TA308317) dilution: 1:500.
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Immunofluorescence analysis of methanol-fixed HeLa, using KLRC1(TA308317) antibody at 1:200 dilution.
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