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Anti-KLK5 GAT Antibody Polyclonal
UltraMAB Antibodies - Validated with 10K Protein Chip
Also for KLK5 (NM_012427)
|DNA immunization. This antibody is specific for the N Terminus Region of the target protein.|
||ELISA: 1:100-1:2000; IHC: 1:400
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody. (Protein A or G Sepharose)
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens kallikrein-related peptidase 5 (KLK5), transcript variant 1|
|KLK-L2; KLKL2; SCTE|
|Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.|
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Immunohistochemical staining of human skin shows strong positivity in the keratinized layer.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.