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Home Antibody All anti-KLC1 antibodies

Anti-KLC1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308531
  • Rabbit polyclonal antibody to KLC1 (kinesin light chain 1)
100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 114 and 441 of KLC1 (Uniprot ID#Q07866)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine) Concentration0.42mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 64kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (97%), Rat (98%), Bovine (99%)

Reference Data

Target NameHomo sapiens kinesin light chain 1 (KLC1), transcript variant 2
Alternative NameKLC; KNS2; KNS2A
Database LinkNP_891553
Entrez Gene 3831 Human
Entrez Gene 16593 Mouse
Entrez Gene 171041 Rat
FunctionConventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq]
Related PathwayDruggable Genome

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Sample (30 ug of whole cell lysate). A: A549. 7.5% SDS PAGE. TA308531 diluted at 1:1000.
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