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Anti-KIT PHOSPHO Antibody
|The antiserum was produced against A synthesized peptide derived from human KIT around the phosphorylation site of Tyrosine 703|
||WB: 1:500-1:2000; IHC: 1:50-1:200
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 1|
|C-Kit; CD117; PBT; SCFR|
|KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.|
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
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Western blot analysis of KIT phosphorylation expression in EGF treated HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.