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Home Antibody All anti-KIT antibodies

Anti-KIT Antibody YB5.B8

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA320403 Mouse Anti-Human CD117 (c-Kit) Purified (25 ug) 25ug $120 3-7 Days
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OriGene Data

Immunogen
Clone NameYB5.B8 Isotype
Species ReactivityHuman Concentration0.5-1mg/ml (lot dependent)
Guaranteed Application * Suggested DilutionsFlow, IHC, IP
BufferAqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Purification Affinity purified

Reference Data

Target NameHomo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 1
Alternative NameC-Kit; CD117; PBT; SCFR
Database LinkNP_000213
Entrez Gene 3815 Human
FunctionThe YB5.B8 monoclonal antibody reacts with human CD117, also known as c-Kit , Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells.
Related PathwayProtein KinaseES Cell Differentiation/IPSTransmembraneStem cell - PluripotencyAdult stem cellsEmbryonic stem cellsDruggable Genome Cytokine-cytokine receptor interactionEndocytosisHematopoietic cell lineageMelanogenesisPathways in cancerAcute myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

 

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