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Home Antibody All anti-KIF5A antibodies

Anti-KIF5A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306457
  • Rabbit Polyclonal KIF5 Antibody
100ug $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenKIF5 antibody was raised against a 20 amino acid peptide from near the center of human KIF5.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 0.5 - 1 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens kinesin family member 5A (KIF5A)
Alternative NameD12S1889; MY050; NKHC; SPG10
Database LinkNP_004975
FunctionThe kinesin superfamily proteins (KIFs) are microtubule-dependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; this antibody recognizes all three. Mutations in one of the isoforms of KIF5 (KIF5A) are thought to be involved in hereditary spastic paraplegias.
Related Pathway

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WB Image
Western blot analysis of KIF5 in K562 cell lysate with KIF5 antibody at (A) 0.5 and (B) 1 ug/mL.
IF Image
Immunocytochemistry of KIF5 in K562 cells with KIF5 antibody at 5 ug/mL.

 

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