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Anti-KIF3A Antibody EPR5087
Also for KIF3A (NM_007054)
|A synthetic peptide corresponding to residues in human KIF3A was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||IP: 1:10 - 1:100; WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens kinesin family member 3A (KIF3A), transcript variant 3|
Entrez Gene 11127 Human
Entrez Gene 16568 Mouse
Entrez Gene 84392 Rat
|KIF3A, a member of the kinesin-like protein family, is a microtubule-based anterograde translocator for membranous organelles (1). The KIF3A motor comprises a heterodimer of the motor proteins KIF3A and KIF3B and an associated protein, KAP3, which binds to the tail ends of KIF3A and KIF3B (2). This heterodimer possesses a plus-end-directed microtubule sliding activity that uses energy derived from ATP hydrolysis. On the other hand, KAP3 links KIF3A/3B with various cargo proteins, including fodrin and the tumor suppressor adenomatous polyposis coli (APC). By binding to fodrin, the KIF3A/3B heterotrimer transports fodrin-associating vesicles that are important for neurite building (3).|
|Druggable Genome |
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Western blot - Anti-KIF3A antibody [EPR5087]; All lanes : Anti-KIF3A antibody [EPR5087] at 1/1000 dilution.Lane 1 : Fetal brain lysate.Lane 2 : SH-SY5Y cell lysate.Lane 3 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-Rabbit IgG at 1/2000 dilution.Predicted band size : 80 kDa.
Other-Anti-KIF3A antibody [EPR5087](TA310642); Equilibrium disassociation constant (KD)..