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Home Antibody All anti-KDR antibodies

Anti-KDR TRUEMAB Antibody Clone OTI12C1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA802572 KDR mouse monoclonal antibody, clone OTI12C1 (formerly 12C1) 100ul $325 In Stock
LC400826 KDR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802572 Carrier-free (BSA/glycerol-free) KDR mouse monoclonal antibody, clone OTI12C1 (formerly 12C1) 100ug $450 3 Days
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 786-1356 of human KDR (NP_002244) produced in HEK293T cell.
Clone NameClone OTI12C1 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR)
Alternative NameCD309; FLK1; VEGFR; VEGFR2
Database LinkNP_002244
Entrez Gene 3791 Human
FunctionVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009].
Related PathwayProtein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionEndocytosisVEGF signaling pathwayFocal adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T lysate (5ug, left lane) and HEK293T cell lysate expressing human recombinant protein fragment corresponding to amino acids 786-1356 of human KDR (NP_002244).
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