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Anti-KDR PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA325609 Rabbit Polyclonal VEGFR2 (Tyr951) Antibody (Phospho-specific) 100ul 325
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OriGene Data

ImmunogenThe antiserum was produced against A synthesized peptide derived from human VEGFR2 around the phosphorylation site of Tyrosine 951
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1:2000; IHC: 1:50-1:200
Predicted MW Explanation 152kDa
BufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.

Reference Data

Target NameHomo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR)
Alternative NameCD309; FLK1; VEGFR; VEGFR2
Database LinkNP_002244
Entrez Gene 3791 Human
Entrez Gene 16542 Mouse
FunctionVEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2.
Related PathwayProtein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionEndocytosisVEGF signaling pathwayFocal adhesion

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of VEGFR2 phosphorylation expression in SK-OV3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.


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