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Anti-KDR PHOSPHO Antibody
|The antiserum was produced against A synthesized peptide derived from human VEGFR2 around the phosphorylation site of Tyrosine 1059|
|Human, Mouse, Rat
|Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
|Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR)|
|CD309; FLK1; VEGFR; VEGFR2|
|VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2.|
Cytokine-cytokine receptor interaction
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Western blot analysis of VEGFR2 phosphorylation expression in Na3VO4 treated HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.