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Home Antibody All anti-KDM5B antibodies
UltraMAB

Anti-KDM5B GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590847
  • Rabbit Polyclonal JARID1B Antibody
50ug 325 In Stock
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OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein (NM_006618).
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application * Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens lysine (K)-specific demethylase 5B (KDM5B)
Alternative NameCT31; JARID1B; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A
Database LinkNP_006609
Entrez Gene 10765 Human
FunctionJARID1B (Jumonji AT-rich interactive domain 1B) is a member of the JARID 1 family of proteins that catalyze the demethylation of histones on lysine. The Jarid 1 family members include JARID1A, JARID1B, JARID1C and JARID1D. The members of this family possess a Jumonji C (JmjC) and Jumonji N (JmjN) domain as well as one ARID (AT-rich interactive domain) and three PHD-type zinc fingers. As histone demethylases, JARID 1 proteins function as transcriptional repressors. JARID1B expression is largely restricted to testis and may play a critical role in tumorigenesis as it has been found to be upregulated in prostate and breast cancer. Alternative names for JARID1B include retinoblastoma-binding protein 2 homolog 1, RBP2-H1, cancer/testis antigen 31, CT31, PLU-1, PUT1, and KDM5B.
Related Pathway

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