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Home Antibody All anti-KDM3A antibodies

Anti-KDM3A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306828
  • Rabbit Polyclonal JMJD1A Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC432099) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for KDM3A (NM_001146688)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenJMJD1A antibody was raised against a 16 amino acid peptide from near the amino terminus of human JMJD1A.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens lysine (K)-specific demethylase 3A (KDM3A), transcript variant 2
Alternative NameJHDM2A; JHMD2A; JMJD1; JMJD1A; TSGA
Database LinkNP_001140160
Entrez Gene 55818 Human
Entrez Gene 104263 Mouse
Entrez Gene 312440 Rat
FunctionThe jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene, but has been found to be expressed in numerous tissues. JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9. It has also been found to be a novel interaction partner with ER71, a transcription factor expressed in the testes of adult mice and during embryogenesis. JMJD1A is also a downstream gene of STAT3, a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells, and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF. These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells. At least two isoforms of JMJD1A are known to exist. This antibody will not cross-react with JMJD1B or JMJD1C.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of JMJD1A in mouse liver tissue lysate with JMJD1A antibody at (A) 1 and (B) 2 µg/ml.
IHC Image
Immunohistochemistry of JMJD1A in rat liver tissue with JMJD1A antibody at 5 ug/ml.

 

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