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Home Antibody All anti-KCP antibodies

Anti-KCP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319056
  • Rabbit polyclonal anti-CRIM2 (KCP) antibody (CT)
100ug 345 3-7 Days
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WB(1)

OriGene Data

ImmunogenCRIM2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human CRIM2.
Clone Name IsotypeRabbit IgG1
Species ReactivityHuman, mouse, rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-2 ug/ml, ELISA
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens kielin/chordin-like protein (KCP), transcript variant 2
Alternative NameCRIM2; KCP1; NET67
Database LinkNP_955381
Entrez Gene 375616 Human
Entrez Gene 333088 Mouse
Entrez Gene 296952 Rat
FunctionCRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-ß1, suppressing activin- and TGF-ß1-dependent transcription.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of CRIM2 in Jurkat cell lysate with CRIM2 antibody at (A) 1 and (B) 2 µg/ml.

 

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