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Home Antibody All anti-KCNMB3 antibodies

Anti-KCNMB3 Antibody S40B-18

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA326402 Mouse monoclonal BK Beta3a Antibody 100µg $325 3-7 Days
LC406784 KCNMB3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenFusion protein amino acids 1-49 (unique N-terminus) of mouse BKBeta3a
Clone NameS40B-18 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~32 kDa. No cross-reactivity against BKBeta1, BKBeta1, BKBeta3b or BKBeta4.

Reference Data

Target NameHomo sapiens potassium channel subfamily M regulatory beta subunit 3 (KCNMB3), transcript variant 1
Alternative NameBKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; KCNMBL; SLO-BETA-3; SLOBETA3
Database LinkNP_741979
Entrez Gene 27094 Human
Entrez Gene 100502876 Mouse
Entrez Gene 310303 Rat
FunctionBK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release . A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia . This has major implications on other physiological processes in tissues other than the brain.
Related PathwayIon Channels: OtherTransmembraneDruggable Genome Vascular smooth muscle contraction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of BKBeta3a in rat brain membrane lysates using a 1:1000 dilution of the antibody
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