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Home Antibody All anti-KCNK12 antibodies

Anti-KCNK12 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319968 Rabbit Polyclonal KCNK12 Antibody 100ug $325 3-7 Days
LC411805 KCNK12 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenKCNK12 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human KCNK12.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferKCNK12 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KCNK12 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens potassium channel, two pore domain subfamily K, member 12 (KCNK12)
Alternative NameK2p12.1; THIK-2; THIK2
Database LinkNP_071338
Entrez Gene 56660 Human
Entrez Gene 210741 Mouse
Entrez Gene 64119 Rat
FunctionKCNK12 Antibody: KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.
Related PathwayIon Channels: PotassiumTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KCNK12 in rat brain tissue lysate with KCNK12 antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.

IHC Image
Immunohistochemistry of KCNK12 in mouse brain tissue with KCNK12 antibody at 5 ug/mL.

IF Image
Immunofluorescence of KCNK12 in mouse brain tissue with KCNK12 antibody at 20 ug/mL.


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