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Home Antibody All anti-KAL1 antibodies

Anti-KAL1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319670
  • Rabbit Polyclonal Anosmin Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400084) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenAnosmin antibody was raised against an 18 amino acid synthetic peptide near the center of human Anosmin.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferAnosmin Antibody is supplied in PBS containing 0.02% sodium azide.
Purification Anosmin Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens Kallmann syndrome 1 sequence (KAL1)
Alternative NameADMLX; HH1; HHA; KAL; KALIG-1; KMS; WFDC19
Database LinkNP_000207
Entrez Gene 3730 Human
FunctionAnosmin Antibody: Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Anosmin in MCF7 cell lysate with Anosmin antibody at 1 ug/mL.
IF Image
Immunofluorescence of Anosmin in MCF7 cells with Anosmin antibody at 20 ug/mL.

 

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