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Home Antibody All anti-JUP antibodies

Anti-JUP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302670
  • Goat Polyclonal Antibody against Plakoglobin / Gamma-catenin
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400807) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for JUP (NM_002230)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-GLRPPYPTADHMLA, from the C Terminus of the protein sequence according to NP_002221, NP_068831.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB 0.2-1µg/ml.
Predicted MW Explanation 81.6 kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens junction plakoglobin (JUP), transcript variant 1
Alternative NameARVD12; CTNNG; DP3; DPIII; PDGB; PKGB
Database LinkNP_002221
Entrez Gene 3728 Human
Entrez Gene 16480 Mouse
Entrez Gene 81679 Rat
Entrez Gene 480522 Dog
FunctionThis gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq].
Related PathwayDruggable Genome Pathways in cancerAcute myeloid leukemiaArrhythmogenic right ventricular cardiomyopathy (ARVC)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302670 staining (0.2µg/ml) of A431 lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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