Home Antibody All anti-JNK1 antibodies
Anti-JNK1 TRUEMAB Antibody clone 4E3
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for JNK1 (NM_002750)
|Human recombinant protein fragment corresponding to amino acids 1-384 of human JNK1 (NP_002741) produced in E.coli.|
|WB, IHC, IF
||WB 1:500, IHC 1:50, IF 1:100,
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-a1|
|JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c|
|JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK1 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of JNK1 by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. JNK1 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of JNK1 gene suggested that it play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.|
EGFR1 Signaling Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
Wnt Signaling Pathway
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY JNK1 (RC218407, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-JNK1.
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-JNK1 mouse monoclonal antibody. (TA500081)
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-JNK1 mouse monoclonal antibody. (TA500081)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-JNK1 mouse monoclonal antibody. (TA500081)
Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-JNK1 mouse monoclonal antibody. (TA500081)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-JNK1 mouse monoclonal antibody. (TA500081)
Anti-JNK1 mouse monoclonal antibody (TA500081) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY JNK1(RC218407).
Immunofluorescent staining of HeLa cells using anti-JNK1 mouse monoclonal antibody (TA500081).