Home Antibody All anti-JMJD6 antibodies
Also for JMJD6 (NM_001081461)
|JMJD6 antibody was raised against a 15 amino acid peptide from near the amino terminus of human JMJD6.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column (Protein A or G Sepharose)
|Homo sapiens jumonji domain containing 6 (JMJD6), transcript variant 1|
|PSR; PTDSR; PTDSR1|
|The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. JMJD6 was initially identified as a membrane protein that participates in phagocytosis but recent studies have shown that it has other functions when it is expressed in the cytosol and nucleus. JMJD6 is thought to play important roles in regulation of development and differentiation as knockdown experiments in mice resulted in neonatal lethality with severe defects in the morphology of numerous organs. JMJD6 also can catalyze the lysyl-hydroxylation of U2AF65, a protein involved with RNA splicing, suggesting that some of the functions attributed to JMJD6 may be due to its regulatory activity of RNA splicing.|
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Western blot analysis of JMJD6 in human brain tissue lysate with JMJD6 antibody at (A) 1 and (B) 2 µg/ml.
Immunohistochemistry of JMJD6 in rat brain tissue with JMJD6 antibody at 2.5 ug/ml.