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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-JAG2 antibodies

Anti-JAG2 Antibody EPR3646

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA307463
  • Rabbit monoclonal antibody against Jagged2(clone EPR3646)
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
Gene NameHomo sapiens jagged 2 (JAG2), transcript variant 1
Synonyms:HJ2; SER2
ImmunogenA synthetic peptide corresponding to the extracellular domain in human Jagged2 was used as an immunogen.
BufferStore at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Clone NameEPR3646 IsotypeRabbit IgG
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB Suggested DilutionsICC: 1:100 - 250, WB: 1:1,000 - 10,000,
BackgroundThe Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch family are transmembrane receptors that are critical for various cell fate decisions. Jagged2 is one of several ligands that activate Notch and related receptors (1). It is also expressed in the heart, placenta and skeletal muscle and to a lesser extend in pancreas (2).
Related Pathway
Delta-Notch Signaling Pathway

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WB Image
Western blot analysis on (A) HeLa, (B) HUVEC, and (C) HT-29 cell lysates using anti-Jagged2 RabMAb .

 

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