Homo sapiens jagged 2 (JAG2), transcript variant 1
Synonyms:
HJ2; SER2
Immunogen
A synthetic peptide corresponding to the extracellular domain in human Jagged2 was used as an immunogen.
Buffer
Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch family are transmembrane receptors that are critical for various cell fate decisions. Jagged2 is one of several ligands that activate Notch and related receptors (1). It is also expressed in the heart, placenta and skeletal muscle and to a lesser extend in pancreas (2).
Related Pathway
Delta-Notch Signaling Pathway
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