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Anti-JAG1 Antibody EPR4290
Also for JAG1 (NM_000214)
|A synthetic peptide corresponding to residues near the C-terminus of human Jagged 1 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
||WB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500; ICC/IF: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens jagged 1 (JAG1)|
|AGS; AHD; AWS; CD339; HJ1; JAGL1|
|Jagged 1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the Jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoiesis (1). |
Delta-Notch Signaling Pathway
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Western blot - Jagged1 antibody [EPR4290]; All lanes : Anti-Jagged1 antibody [EPR4290] at 1/10000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : NIH:OVCAR-3 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 134 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Jagged1 antibody [EPR4290]; ab109536 at 1/250 dilution staining Jagged1 in paraffin-embedded bladder cancer tissue by Immunohistochemistry.
Immunocytochemistry/ Immunofluorescence - Jagged1 antibody [EPR4290]; ab109536 at 1/100 dilution staining Jagged1 in HeLa cells by Immunofluorescence.