Anti-JAG1 Antibody, EPR4290

Also for JAG1 (NM_000214)

Gene Name	Homo sapiens jagged 1 (JAG1)
Synonyms:	AGS; AHD; AWS; CD339; HJ1; JAGL1
Immunogen	A synthetic peptide corresponding to residues near the C-terminus of human Jagged 1 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR4290	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250; IP: 1:10 - 100;
Background	Jagged 1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the Jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoiesis (1).
Related Pathway	Delta-Notch Signaling Pathway

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WB Image

Western blot analysis on (A) HepG2 and (B) NIH:OVCAR-3 cell lysates using anti-Jagged 1 RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded bladder cancer tissue using anti-Jagged 1 RabMAb.

IF Image

Immunofluorescent staining of HeLa cells using anti-Jagged 1 RabMAb.

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Anti-JAG1 Antibody EPR4290

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