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Home Antibody All anti-JAG1 antibodies

Anti-JAG1 Antibody EPR4290

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310959
  • Rabbit Monoclonal antibody against Jagged 1 (JAG1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400079) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for JAG1 (NM_000214)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human Jagged 1 was used as an immunogen.
Clone NameEPR4290 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 134 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens jagged 1 (JAG1)
Alternative NameAGS; AHD; AWS; CD339; HJ1; JAGL1
Database LinkNP_000205
Entrez Gene 182 Human
FunctionJagged 1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the Jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoiesis (1).
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Notch signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Jagged1 antibody [EPR4290]; All lanes : Anti-Jagged1 antibody [EPR4290] at 1/10000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : NIH:OVCAR-3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 134 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Jagged1 antibody [EPR4290]; TA310959 at 1/250 dilution staining Jagged1 in paraffin-embedded bladder cancer tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Jagged1 antibody [EPR4290]; TA310959 at 1/100 dilution staining Jagged1 in HeLa cells by Immunofluorescence.

 

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