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Home Antibody All anti-ITPR1 antibodies

Anti-ITPR1 Antibody EPR4536

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310635
  • Rabbit Monoclonal antibody against ITPR1
100ul $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ITPR1 was used as an immunogen.
Clone NameEPR4536 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; FC: 1:10 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1
Alternative NameACV; CLA4; INSP3R1; IP3R; IP3R1; PPP1R94; SCA15; SCA16; SCA29
Database LinkNP_001093422
Entrez Gene 3708 Human
FunctionITPR1 is an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders.
Related PathwayTransmembraneDruggable Genome Calcium signaling pathwayPhosphatidylinositol signaling systemOocyte meiosisVascular smooth muscle contractionGap junctionLong-term potentiationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-ITPR1 antibody [EPR4536]; All lanes : Anti-IP3 receptor antibody [EPR4536] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HuT78 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 314 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ITPR1 antibody [EPR4536]; TA310635, at 1/50, staining ITPR1 in paraffin-embedded Human brain tissue by immunohistochemistry.
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