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Anti-ITPR1 Antibody EPR4536

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

IHC(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in human ITPR1 was used as an immunogen.
Clone Name	EPR4536	Isotype
Species Reactivity	Human	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; IP: 1:10 - 100;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1
Alternative Name	INSP3R1; IP3R; IP3R1; SCA15; SCA16; SCA29
Database Link	NP_001093422
Function	ITPR1 is an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in ITPR1 cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders.
Related Pathway	Hemostasis Signaling by GPCR

Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • ITPR1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • ITPR1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Itpr1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • ITPR1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Itpr1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1 as transfection-ready DNA Related cDNA Clones • Homo sapiens inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1), transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)