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Anti-ITM2B TRUEMAB Antibody clone 1C11
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for ITM2B (NM_021999)
|Full length human recombinant protein of human ITM2B (NP_068839) produced in HEK293T cell.|
|WB, IHC, FC
||WB 1:2000, IHC 1:150, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens integral membrane protein 2B (ITM2B)|
|ABRI; BRI; BRI2; BRICD2B; E25B; E3-16; FBD; imBRI2|
Entrez Gene 9445 Human
|Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq]. |
|TransmembraneDruggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ITM2B (RC202377, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ITM2B.
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ITM2B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502734)
Flow cytometric Analysis of Hela cells, using anti-ITM2B antibody(TA502734),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
Flow cytometric Analysis of Jurkat cells, using anti-ITM2B antibody(TA502734),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).