OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-ITGAM antibodies

Anti-ITGAM Antibody EPR1344

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307682
  • Rabbit monoclonal antibody against CD11b/ITAM (clone EPR1344 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424601) , 20ug Explanation
100ul $325 In Stock
Add to Shopping Cart
spacer
WB(1)
IHC(2)
spacer
Also for ITGAM (NM_000632)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD11b was used as an immunogen.
Clone NameEPR1344 IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:5000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; FC: 1:100
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM), transcript variant 2
Alternative NameCD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6
Database LinkNP_000623
Entrez Gene 3684 Human
Entrez Gene 16409 Mouse
FunctionIntegrin alpha-M (ITAM, ITGAM, CD11b, MAC-1 alpha subunit, CR3 alpha chain) belongs to integrin alpha chain family and it is predominately presented in human myeloid cells, NK1 cells, monocytes, and granulocytes. The alpha subunit of ITAM/beta-2 complex (CD11b/CD18, Mac-1), is complex is a receptor for fibrinogen (binding to P1 and P1 peptides of gamma chain), factor X, and ICAM1. ITAM/beta-2 is implicated in adhesive interactions of monocytes, macrophages, and granulocytes. It is also linked to mediation of complement-coated particle uptake (2).
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Hematopoietic cell lineageLeukocyte transendothelial migrationRegulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-CD11b antibody [EPR1344]; All lanes : Anti-CD11b [EPR1344] antibody at 1/1000 dilution.Lane 1 : THP1 cell lysate treated with TPA.Lane 2 : TF1 cell lysate .Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 127 kDa.
spacer
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD11b antibody [EPR1344]; Immunohistochemical analysis of CD11b in paraffin embedded Human tonsil tissue, using TA307682 at a dilution of 1/100.
spacer
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD11b antibody [EPR1344]; Immunohistochemical analysis of CD11b in paraffin embedded Human spleen tissue, using TA307682 at a dilution of 1/100.
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title