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Anti-ITGAM Antibody EPR1344
Also for ITGAM (NM_000632)
|A synthetic peptide corresponding to residues in human CD11b was used as an immunogen.|
||Tissue culture supernatant
|Mouse, Human (Does not react with: Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:5000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; FC: 1:100
|Does not react with Rat. Is unsuitable for IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Is unsuitable for IP.
|Homo sapiens integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM), transcript variant 2|
|CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6|
Entrez Gene 3684 Human
Entrez Gene 16409 Mouse
|Integrin alpha-M (ITAM, ITGAM, CD11b, MAC-1 alpha subunit, CR3 alpha chain) belongs to integrin alpha chain family and it is predominately presented in human myeloid cells, NK1 cells, monocytes, and granulocytes. The alpha subunit of ITAM/beta-2 complex (CD11b/CD18, Mac-1), is complex is a receptor for fibrinogen (binding to P1 and P1 peptides of gamma chain), factor X, and ICAM1. ITAM/beta-2 is implicated in adhesive interactions of monocytes, macrophages, and granulocytes. It is also linked to mediation of complement-coated particle uptake (2). |
|ES Cell Differentiation/IPSTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Hematopoietic cell lineageLeukocyte transendothelial migrationRegulation of actin cytoskeleton|
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Western blot - Anti-CD11b antibody [EPR1344]; All lanes : Anti-CD11b [EPR1344] antibody at 1/1000 dilution.Lane 1 : THP1 cell lysate treated with TPA.Lane 2 : TF1 cell lysate .Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 127 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD11b antibody [EPR1344]; Immunohistochemical analysis of CD11b in paraffin embedded Human tonsil tissue, using TA307682 at a dilution of 1/100.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD11b antibody [EPR1344]; Immunohistochemical analysis of CD11b in paraffin embedded Human spleen tissue, using TA307682 at a dilution of 1/100.