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Home Antibody All anti-ITGAM antibodies

Anti-ITGAM Antibody EPR1344

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307682
  • Rabbit monoclonal antibody against CD11b/ITAM (clone EPR1344 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424601) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for ITGAM (NM_000632)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD11b was used as an immunogen.
Clone NameEPR1344 IsotypeTissue culture supernatant
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:5000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; FC: 1:100
BufferDoes not react with Rat. Is unsuitable for IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM), transcript variant 2
Alternative NameCD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6
Database LinkNP_000623
Entrez Gene 3684 Human
Entrez Gene 16409 Mouse
FunctionIntegrin alpha-M (ITAM, ITGAM, CD11b, MAC-1 alpha subunit, CR3 alpha chain) belongs to integrin alpha chain family and it is predominately presented in human myeloid cells, NK1 cells, monocytes, and granulocytes. The alpha subunit of ITAM/beta-2 complex (CD11b/CD18, Mac-1), is complex is a receptor for fibrinogen (binding to P1 and P1 peptides of gamma chain), factor X, and ICAM1. ITAM/beta-2 is implicated in adhesive interactions of monocytes, macrophages, and granulocytes. It is also linked to mediation of complement-coated particle uptake (2).
Related Pathway
Focal Adhesion
Hematopoietic cell lineage
Hemostasis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CD11b antibody [EPR1344]; All lanes : Anti-CD11b [EPR1344] antibody at 1/1000 dilution.Lane 1 : THP1 cell lysate treated with TPA.Lane 2 : TF1 cell lysate .Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 127 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD11b antibody [EPR1344]; Immunohistochemical analysis of CD11b in paraffin embedded Human tonsil tissue, using TA307682 at a dilution of 1/100.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD11b antibody [EPR1344]; Immunohistochemical analysis of CD11b in paraffin embedded Human spleen tissue, using TA307682 at a dilution of 1/100.

 

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