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Home Antibody All anti-ITGA2B antibodies

Anti-ITGA2B Antibody EPR4330

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310956
  • Rabbit Monoclonal antibody against CD41 / Integrin alpha 2b (ITGA2B)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424734) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for ITGA2B (NM_000419)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain in human CD41 / Integrin alpha 2b was used as an immunogen.
Clone NameEPR4330 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 59% Tris glycine, 40% Glycerol, 0.88% Sodium chloride, 0.05% BSA
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B)
Alternative NameBDPLT16; BDPLT2; CD41; CD41B; GP2B; GPIIb; GT; GTA; HPA3; PPP1R93
Database LinkNP_000410
Entrez Gene 3674 Human
FunctionCD41 is also known as integrin alpha 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD41 / Integrin alpha 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling.
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Focal adhesionECM-receptor interactionHematopoietic cell lineageRegulation of actin cytoskeletonPathways in cancerSmall cell lung cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-CD41/Integrin alpha 2b antibody [EPR4330]; All lanes : Anti-CD41/Integrin alpha 2b antibody [EPR4330] at 1/1000 dilution.Lane 1 : Human platelet lysate.Lane 2 : Human fetal liver lysate.Lane 3 : Human placenta lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti rabbit at 1/2000 dilution.Predicted band size : 113 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD41/Integrin alpha 2b antibody [EPR4330]; Immunohistochemical analysis of paraffin-embedded Human spleen tissue labelling CD41/Integrin alpha 2b with TA310956 at 1/100 dilution.

 

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