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Home Antibody All anti-IRS2 antibodies

Anti-IRS2 Antibody EP976Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303754
  • Rabbit monoclonal antibody against IRS-2 (Pan)(EP976Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418459) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Ser1203 of human IRS-2 was used as an immunogen.
Clone NameEP976Y IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:100000; IP: 1:50; IHC-P: Use at an assay dependent dilution
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens insulin receptor substrate 2 (IRS2)
Alternative NameIRS-2
Database LinkNP_003740
FunctionThis gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq].
Related Pathway
Adipogenesis

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WB Image
Western blot - IRS2 antibody [EP976Y]; Anti-IRS2 antibody [EP976Y] at 1/100000 dilution + 293 cell lysate at 10 µg.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 137 kDa.Observed band size : 185 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - IRS2 antibody [EP976Y]; Immunohistochemical staining of paraffin-embedded human kidney using TA303754 at a dilution of 1/100-1/250.

 

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