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Anti-IRS2 Antibody EP903Y


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against IRS-2(EP903Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418459) , 20ug Explanation
100ul 325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human IRS-2 was used as an immunogen.
Clone NameEP903Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:100,000; IHC: 1:50-100; ICC: 1:250 100; IP: 1:50
Predicted MW Explanation 137 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens insulin receptor substrate 2 (IRS2)
Alternative NameIRS-2
Database LinkNP_003740
Entrez Gene 8660 Human
FunctionThis gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq].
Related PathwayDruggable Genome Neurotrophin signaling pathwayInsulin signaling pathwayAdipocytokine signaling pathwayType II diabetes mellitus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - IRS2 antibody [EP903Y]; Anti-IRS2 antibody [EP903Y] at 1/100000 dilution + 293 cell lysate at 10ug/lane, plus insulin .Secondary.Goat-anti rabbit, HRP labelled, at 1/2000 dilution.Predicted band size : 137 kDa.Observed band size : 160 kDa .Additional bands at : 50 kDa (possible non-specific binding).
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - IRS2 antibody [EP903Y]; This image shows human cervical carcinoma stained with TA303753 at 1/50 dilution.


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