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Home Antibody All anti-IRS1 antibodies

Anti-IRS1 PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322592
  • Anti-IRS1 (Phospho-Ser312) Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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WB(1)

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of serine 312 (A-T-S(p)-P-A) derived from Human IRS-1.
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1000
Predicted MW Explanation 180kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens insulin receptor substrate 1 (IRS1)
Alternative NameHIRS-1
Database LinkNP_005535
Entrez Gene 3667 Human
Entrez Gene 16367 Mouse
Entrez Gene 25467 Rat
FunctionMay mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit
Related PathwayDruggable Genome Neurotrophin signaling pathwayInsulin signaling pathwayAdipocytokine signaling pathwayType II diabetes mellitus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 180 kDa . Positive control: 293 cells untreated or treated with insulin lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: 293 cells untreated with insulin lysate Lane2: 293 cells treated with insulin lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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