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Home Antibody All anti-IRF6 antibodies

Anti-IRF6 TRUEMAB Antibody Clone OTI2A12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA503345 IRF6 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12) 100ul $325 In Stock
LC401852 IRF6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503345 Carrier-free (BSA/glycerol-free) IRF6 mouse monoclonal antibody, clone OTI2A12 (formerly 2A12) 100ug $450 3-4 weeks
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WB(1)
IHC(4)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human IRF6(NP_006138) produced in HEK293 cell.
Clone NameClone OTI2A12 IsotypeIgG2b
Species ReactivityHuman Concentration0.2 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 52.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interferon regulatory factor 6 (IRF6), transcript variant 1
Alternative NameLPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
Database LinkNP_006138
Entrez Gene 3664 Human
FunctionThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. [provided by RefSeq].
Related PathwayES Cell Differentiation/IPSTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IRF6 (RC201579, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IRF6.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503345)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503345)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503345)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IRF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503345)
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Anti-IRF6 mouse monoclonal antibody (TA503345) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IRF6(RC201579).
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HEK293T cells transfected with either RC201579 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-IRF6 antibody(TA503345), and then analyzed by flow cytometry.
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