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Home Antibody All anti-IRAK4 antibodies

Anti-IRAK4 Antibody Y279

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303793
  • Rabbit monoclonal antibody against IRAK4, N-term(Y279)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402503) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for IRAK4 (NM_016123)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-term of human IRAK-4 was used as immunogen.
Clone NameY279 IsotypeIgG fraction
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:50 - 1:100; IHC-P: Use a concentration of 1 ug/ml; WB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2
Alternative NameIPD1; IRAK-4; NY-REN-64; REN64
Database LinkNP_057207
FunctionThis gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeq].
Related Pathway
Toll-like receptor signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - IRAK4 antibody [Y279]; Anti-IRAK4 antibody [Y279] at 1/500 dilution + Jurkat cell lysate.Observed band size : 52 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IRAK4 antibody [Y279]; IHC image ofab32511 staining in human spleenformalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with TA303793, 1ug/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

 

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