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Home Antibody All anti-IRAK1 antibodies

Anti-IRAK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319667
  • Mouse IRAK Monoclonal Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC422494) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for IRAK1 (NM_001025242)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein corresponding to amino acids 618 - 712 of human IRAK.
Clone Name IsotypeIgG1
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 2.5 ug/ml
BufferIRAK Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IRAK Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Reference Data

Target NameHomo sapiens interleukin-1 receptor-associated kinase 1 (IRAK1), transcript variant 2
Alternative NameIRAK; pelle
Database LinkNP_001020413
FunctionIRAK Monoclonal Antibody: Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and LPS. A serine/threonine protein kinase associated with IL-1 receptor (IRAK) and its homologue mouse pelle-like protein kinase (mPLK) were identified recently. IRAK is associated with the IL-1 receptor subunits IL-1RI and IL-1RAcP after IL-1 binding and serves as a signaling molecule to mediate IL-1 response. IRAK mediates a signaling cascade leading to NF-κB activation by members in IL-1 family including IL-1 and a novel cytokine IL-18 (also termed IGIF).
Related Pathway
Toll-like receptor signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IRAK in HeLa lysates with IRAK antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of IRAK in rat liver tissue with IRAK antibody at 2.5 ug/mL.

 

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