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Home All anti-INSR antibodies

Anti-INSR Phospho Antibody EP351(2)Y

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA303549
  • Rabbit monoclonal antibody against INSR/IGF-R (pY1185) Phospho (EP351(2)Y ) (phospho-specific)
100µl $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)

OriGene Data

ImmunogenA phospho synthetic peptide corresponding to residues surrounding Tyrosine 1185 of human INSR was used as an immunogen. This antibody detects INSR phosphorylated at Tyrosine 1185.
Clone NameEP351(2)Y IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:500; ICC: 1:100; IP: 1:20
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens insulin receptor (INSR), transcript variant 2
Alternative NameCD220; HHF5
Database LinkNP_001073285
FunctionAfter removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway
Adherens junction

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WB Image
Western blot analysis on HepG2 cell lysates using anti-Phospho-INSR/IGF-R (pY1185) RabMAb (TA303549), 1:500 dilution. Cells were either (A) untreated or (B) treated with insulin.

 

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