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Anti-INSR Phospho Antibody EP351(2)Y
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Also for INSR (NM_001079817)
|A phospho synthetic peptide corresponding to residues surrounding Tyrosine 1185 of human INSR was used as an immunogen. This antibody detects INSR phosphorylated at Tyrosine 1185.|
||WB: 1:500; ICC: 1:100; IP: 1:20
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens insulin receptor (INSR), transcript variant 2|
|After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
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Western blot analysis on HepG2 cell lysates using anti-Phospho-INSR/IGF-R (pY1185) RabMAb (TA303549), 1:500 dilution. Cells were either (A) untreated or (B) treated with insulin.