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Anti-INS Antibody EPR3074
|A synthetic peptide corresponding to residues in human Insulin was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||IHC-P: 1:250 - 1:500
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IP or WB.
|Homo sapiens insulin (INS), transcript variant 1|
|IDDM2; ILPR; IRDN; MODY10|
|Insulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and an A chain linked by two disulfide bonds (1). It is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a C-peptide (2). Defects in insulin results in diabetes mellitus (1).|
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Other-Anti-Insulin antibody [EPR3074](ab133281); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Insulin antibody [EPR3074]; Immunohistochemical analysis of paraffin-embedded Human pancreas tissue labelling Insulin with ab133281 at 1/250 dilution.