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Home Antibody All anti-INS antibodies

Anti-INS Antibody EPR3074

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307744
  • Rabbit monoclonal antibody against Insulin(clone EPR3074)
100ul 325 3-7 Days
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IHC(1)
Assay(1)
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Also for INS (NM_000207)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Insulin was used as an immunogen.
Clone NameEPR3074 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *ASSAY, IHC Suggested DilutionsIHC-P: 1:250 - 1:500
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IP or WB.

Reference Data

Target NameHomo sapiens insulin (INS), transcript variant 1
Alternative NameIDDM1; IDDM2; ILPR; IRDN; MODY10
Database LinkNP_000198
FunctionInsulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and an A chain linked by two disulfide bonds (1). It is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a C-peptide (2). Defects in insulin results in diabetes mellitus (1).
Related Pathway
Adipogenesis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Assay Image
Other-Anti-Insulin antibody [EPR3074](TA307744); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Insulin antibody [EPR3074]; Immunohistochemical analysis of paraffin-embedded Human pancreas tissue labelling Insulin with TA307744 at 1/250 dilution.

 

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