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Home Antibody All anti-INS antibodies

Anti-INS Antibody EPR3075

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307743
  • Rabbit monoclonal antibody against Insulin(clone EPR3075)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400078) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for INS (NM_000207)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Insulin was used as an immunogen.
Clone NameEPR3075 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens insulin (INS), transcript variant 1
Alternative NameIDDM1; IDDM2; ILPR; IRDN; MODY10
Database LinkNP_000198
FunctionInsulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and an A chain linked by two disulfide bonds (1). It is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a C-peptide (2). Defects in insulin results in diabetes mellitus (1).
Related Pathway
Adipogenesis

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - C Peptide antibody [EPR3075]; Anti-C Peptide antibody [EPR3075] at 1/1000 dilution + Human fetal pancreas lysate at 10 µg.Predicted band size : 12 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C Peptide antibody [EPR3075]; TA307743 at 1/100 dilution staining C peptide in Human pancreas by Immunohistochemistry, Paraffin-embedded tissue.

 

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