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Home Antibody All anti-INS antibodies

Anti-INS Antibody EPR3075


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307743 Rabbit monoclonal antibody against Insulin(clone EPR3075) 100ul $325 In Stock
LC400078 INS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Insulin was used as an immunogen.
Clone NameEPR3075 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens insulin (INS), transcript variant 1
Alternative NameIDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10
Database LinkNP_000198
Entrez Gene 3630 Human
FunctionInsulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and an A chain linked by two disulfide bonds (1). It is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a C-peptide (2). Defects in insulin results in diabetes mellitus (1).
Related PathwaySecreted ProteinES Cell Differentiation/IPSDruggable Genome Oocyte meiosisRegulation of autophagymTOR signaling pathwayRegulation of actin cytoskeletonInsulin signaling pathwayProgesterone-mediated oocyte maturationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - C Peptide antibody [EPR3075]; Anti-C Peptide antibody [EPR3075] at 1/1000 dilution + Human fetal pancreas lysate at 10 ug.Predicted band size : 12 kDa.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C Peptide antibody [EPR3075]; TA307743 at 1/100 dilution staining C peptide in Human pancreas by Immunohistochemistry, Paraffin-embedded tissue.


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