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Anti-INS Antibody EPR3075
|A synthetic peptide corresponding to residues in human Insulin was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt,ICC or IP.
|Homo sapiens insulin (INS), transcript variant 1|
|IDDM2; ILPR; IRDN; MODY10|
|Insulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and an A chain linked by two disulfide bonds (1). It is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a C-peptide (2). Defects in insulin results in diabetes mellitus (1).|
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Western blot - C Peptide antibody [EPR3075]; Anti-C Peptide antibody [EPR3075] at 1/1000 dilution + Human fetal pancreas lysate at 10 µg.Predicted band size : 12 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - C Peptide antibody [EPR3075]; TA307743 at 1/100 dilution staining C peptide in Human pancreas by Immunohistochemistry, Paraffin-embedded tissue.