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Anti-INHBB Antibody EPR2788(2)
Also for INHBB (NM_002193)
|A synthetic peptide corresponding to residues in human Inhibin beta B was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IHC-P or IP.
|Homo sapiens inhibin, beta B (INHBB)|
|The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the inhibin beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion (1).|
Cytokine-cytokine receptor interaction
TGF Beta Signaling Pathway
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Western blot - Anti-Inhibin beta B antibody [EPR2788(2)]; All lanes : Anti-Inhibin beta B antibody [EPR2788(2)] at 1/1000 dilution.Lane 1 : Mouse brain lysate.Lane 2 : Rat brain lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.Observed band size : 52 kDa .
Western blot - Anti-Inhibin beta B antibody [EPR2788(2)]; Anti-Inhibin beta B antibody [EPR2788(2)] at 1/1000 dilution + Human Inhibin beta B recombinant protein (mature form: 17 kDa) (10 ng).Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.
Other-Anti-Inhibin beta B antibody [EPR2788(2)](TA310631); Equilibrium disassociation constant (KD)..