Home Antibody All anti-INHBA antibodies
Also for INHBA (NM_002192)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 362 and 423 of Inhibin beta-A|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens inhibin, beta A (INHBA)|
|The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq]|
Cytokine-cytokine receptor interaction
TGF Beta Signaling Pathway
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Sample(30 ug whole cell lysate) A:H1299 B:HeLa S3 C:HepG2 (anti-INHBA antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded CLEAR CELL OVCA xenograft, using Inhibin beta A(anti-INHBA antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Inhibin beta-A (anti-INHBA antibody) antibody at 1:200 dilution.