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Anti-INHA Antibody EPY2782
Also for INHA (NM_002191)
|A synthetic peptide corresponding to residues near the N-terminus of human Inhibin alpha chain was used as an immunogen. 20/23 kDa bands consist of the mature alpha chain. 50/53 kDa bands are the entire proprotein.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:2000; FC: 1:300
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for IHC-P or IP.
|Homo sapiens inhibin, alpha (INHA)|
|A-inhibin subunit; inhibin alpha subunit; inhibin, alpha|
|Inhibin alpha chain is a peptide hormone that inhibits the secretion of follitropin by the pituitary gland. Inhibins and activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition (1). Granulosa-cell tumors produce inhibin and since serum inhibin levels reflect the size of the tumor, measurements of inhibin can be used as a marker for primary as well as recurrent disease (2). In the malignant regions of tissue from men with high grade prostate cancer, the expression of the inhibin alpha-subunit gene is suppressed and was not detectable in poorly differentiated tumor cells. These results demonstrate that in contrast to ovarian granulosa cell tumors, inhibin alpha chain is not expressed in poorly differentiated prostate cancer (3). |
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Western blot - Inhibin alpha antibody [EPY2782]; All lanes : Anti-Inhibin alpha antibody [EPY2782] at 1/2000 dilution.Lane 1 : Human Adrenal gland lysate.Lane 2 : HeLa cell lysate.Lane 3 : Human placenta lysate.Lane 4 : LNCaP lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP goat anti rabbit at 1/2000 dilution.Predicted band size : 40 kDa.Observed band size : 40,50 kDa .Additional bands at : 42 kDa. We are unsure as to the identity of these extra bands.