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Anti-ING2 Antibody EPR4597
Also for ING2 (NM_001564)
|A recombinant protein fragment corresponding to residues in human ING2 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:1000 - 1:2000; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens inhibitor of growth family, member 2 (ING2), transcript variant 1|
|ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis (1). ING2 is involved in p53/TP53 activation, by enhancing acetylation of p53/TP53. ING2 is a component of a mSin3A-like corepressor complex, which is involved in deacetylation of nucleosomal histones (2).|
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Western blot - ING2 antibody [EPR4597]; All lanes : Anti-ING2 antibody [EPR4597] at 1/10000 dilution.Lane 1 : T47-D cell lysate.Lane 2 : HepG2 cell lysate .Lane 3 : HT-1080 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 33 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ING2 antibody [EPR4597]; Immunohistochemical analysis of ING2 expression in formalin-fixed, paraffin-embedded Human kidney tissue using TA310630 at 1/1000 dilution.