OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431.
[anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780.
[SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052
[anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210.
[NPR3] View All Citations >>
Home All anti-IMPDH2 antibodies
Anti-IMPDH2 Antibody EPR8365(B)
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
Also for IMPDH2 (NM_000884)
Homo sapiens IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2) IMPD2; IMPDH-II A synthetic peptide corresponding to residues on the C-terminus in human IMPDH2 was used as an immunogen. Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
EPR8365(B)
Human, Mouse, Rat
(Protein A or G Sepharose )
WB, IHC, IF
WB: 1:1,000 - 10,000;
IMPDH2 is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation (1).
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WB Image
Western blot analysis on (A) HepG2, (B) A549, (C) MCF-7, (D) HeLa, and (E) K562 cell lysates using anti-IMPDH2 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-IMPDH2 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded breast carcinoma tissue using anti-IMPDH2 RabMAb.
IF Image
Western blot analysis on (A) HepG2, (B) A549, (C) MCF-7, (D) HeLa, and (E) K562 cell lysates using anti-IMPDH2 RabMAb.
IF Image
Immunofluorescent staining of MCF-7 cells using anti-IMPDH2 RabMAb.
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