Home Antibody All anti-IMPDH2 antibodies
Also for IMPDH2 (NM_000884)
|Peptide with sequence KEEEHDCFLEEI, from the internal region of the protein sequence according to NP_000875.2.|
|Test: Human. Expected from seq similarity: Human
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens IMP (inosine 5'-monophosphate) dehydrogenase 2 (IMPDH2)|
Entrez Gene 3615 Human
|This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq]. |
|Druggable Genome Purine metabolismDrug metabolism - other enzymesMetabolic pathways|
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TA305796 (1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.