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Home Antibody All anti-IL6R antibodies

Anti-IL6R TRUEMAB Antibody Clone 1B5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506855
  • IL6R mouse monoclonal antibody,clone 1B5
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400192) , 20ug Explanation
100ul 325 In Stock
CF506855
  • Carrier-free (BSA/glycerol-free) IL6R mouse monoclonal antibody,clone 1B5
100ug $450 8-10 Days
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
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Also for IL6R (NM_000565)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IL6R(NP_000556) produced in HEK293T cell.
Clone NameClone 1B5 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 49.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interleukin 6 receptor (IL6R), transcript variant 1
Alternative NameCD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ
Database LinkNP_000556
Entrez Gene 3570 Human
FunctionThis gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathwayHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL6R (RC221874, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL6R.

 

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