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Home Antibody All anti-IL4 antibodies

Anti-IL4 Antibody EPR1118Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303545
  • Rabbit monoclonal antibody against IL-4 (EPR1118Y )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424622) , 20ug
100ul $325 In Stock
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WB(1)
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Also for IL4 (NM_000589)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IL-4 was used as an immunogen.
Clone NameEPR1118Y IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; ICC: 1:500
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens interleukin 4 (IL4), transcript variant 1
Alternative NameBCGF-1; BCGF1; BSF-1; BSF1; IL-4
Database LinkNP_000580
FunctionThe protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq].
Related Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway

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WB Image
Western blot - IL4 antibody [EPR1118Y]; Anti-IL4 antibody [EPR1118Y] at 1/2000 dilution + Human tonsil lysate at 10 µg.Secondary.goat anti rabbit HRP at 1/2000 dilution.Predicted band size : 17 kDa.Observed band size : 14 kDa .

 

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