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Home Antibody All anti-IL4 antibodies

Anti-IL4 Antibody EPR1118Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303545 Rabbit monoclonal antibody against IL-4 (EPR1118Y ) 100ul $325 In Stock
LC424622 IL4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IL-4 was used as an immunogen.
Clone NameEPR1118Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; ICC: 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens interleukin 4 (IL4), transcript variant 1
Alternative NameBCGF-1; BCGF1; BSF-1; BSF1; IL-4
Database LinkNP_000580
Entrez Gene 3565 Human
FunctionThe protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq].
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathwayHematopoietic cell lineageT cell receptor signaling pathwayFc epsilon RI signaling pathwayAsthmaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - IL4 antibody [EPR1118Y]; Anti-IL4 antibody [EPR1118Y] at 1/2000 dilution + Human tonsil lysate at 10 ug.Secondary.goat anti rabbit HRP at 1/2000 dilution.Predicted band size : 17 kDa.Observed band size : 14 kDa .


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