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Home Antibody All anti-IL23A antibodies

Anti-IL23A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306315
  • Rabbit Polyclonal IL-23 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402570) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for IL23A (NM_016584)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenIL-23 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-23.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 23, alpha subunit p19 (IL23A)
Alternative NameIL-23; IL-23A; IL23P19; P19; SGRF
Database LinkNP_057668
Entrez Gene 51561 Human
Entrez Gene 83430 Mouse
FunctionLike interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of IL-23 in mouse pancreas tissue lysate with IL-23 antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of IL-23 in mouse pancreas tissue with IL-23 antibody at 2 ug/ml.

 

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