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Home Antibody All anti-IL2 antibodies

Anti-IL2 Antibody EPR2780

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307686 Rabbit monoclonal antibody against IL-2 (clone EPR2780 ) 100ul $325 In Stock
LC424619 IL2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IL-2 was used as an immunogen.
Clone NameEPR2780 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:500 - 1:1000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens interleukin 2 (IL2)
Alternative NameIL-2; lymphokine; TCGF
Database LinkNP_000577
Entrez Gene 3558 Human
FunctionInterleukin-2 (IL-2) is an immunoregulatory cytokine that functions as a growth factor and central regulator in the immune system (1, 2). It participates in modulating the immune response by helping control the rate of clonal expansion of lymphocytes (3). IL-2 acts through a quaternary receptor signaling complex containing alpha, beta, and common gamma chain receptors (1). IL-2 is produced by T-cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial for regulation of the immune response. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (4).
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathwayT cell receptor signaling pathwayType I diabetes mellitusAutoimmune thyroid diseaseAllograft rejectionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - IL2 antibody [EPR2780]; All lanes : Anti-IL2 antibody [EPR2780] at 1/1000 dilution.Lane 1 : Human thymus lysate.Lane 2 : PBMC lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 18 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - IL2 antibody [EPR2780]; TA307686 at 1/250 dilution staining IL2 in Formalin-fixed, Paraffin-embedded Human tonsil tissue. Detection: DAB staining.
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