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Anti-IL1B GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for IL1B (NM_000576)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|WB, ELISA, IHC
|| WB 1:20000, IHC 1:150,ELISA 1:100-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens interleukin 1, beta (IL1B)|
|IL-1; IL1-BETA; IL1F2|
|Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.|
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
MAPK signaling pathway
Toll-like receptor signaling pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL1B (RC202079, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL1B.
ELISA: IL1 beta Antibody - Affinity Purified
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-IL1B rabbit polyclonal antibody. (TA590024)
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-IL1B rabbit polyclonal antibody. (TA590024)