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Home Antibody All anti-IL1B antibodies
UltraMAB

Anti-IL1B GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590024
  • Rabbit Polyclonal IL1 beta Antibody
100ug 325 In Stock
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WB(1)
IHC(2)
ELISA(1)
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Also for IL1B (NM_000576)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested Dilutions WB 1:20000, IHC 1:150,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens interleukin 1, beta (IL1B)
Alternative NameIL-1; IL1-BETA; IL1F2
Database LinkNP_000567
Entrez Gene 3553 Human
FunctionInterleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence.
Related PathwaySecreted ProteinDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionApoptosisToll-like receptor signaling pathwayNOD-like receptor signaling pathwayCytosolic DNA-sensing pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL1B (RC202079, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL1B.
ELISA Image
ELISA: IL1 beta Antibody - Affinity Purified
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-IL1B rabbit polyclonal antibody. (TA590024)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-IL1B rabbit polyclonal antibody. (TA590024)

 

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