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Anti-IL1B TrueMAB Antibody Clone 3E1
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for IL1B (NM_000576)
|Full length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell.|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, IHC, IF
|| WB 1:1000~4000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens interleukin 1, beta (IL1B)|
|IL-1; IL1-BETA; IL1F2|
|The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]. |
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
MAPK signaling pathway
Toll-like receptor signaling pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL1B (RC202079, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL1B.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IL1B mouse monoclonal antibody. (TA506443)
Anti-IL1B mouse monoclonal antibody (TA506443) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IL1B(RC202079).